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Impotence treatment begins with a brief anatomy lesson. To understand how to go about fighting erectile dysfunction, it is necessary first to understand the erection, its primary parts and how they function together. But even if erectile problems are not a concern, the mechanisms of the erection should be familiar to every man, just as heavy machinery operators need to understand how their tools work.

What Happens During an Erection

The erectile tissue in the penis is like a sponge, and it becomes turgid (hard, erect) when it has absorbed all the blood it can. Consider balloons, and how much firmer they are inflated as opposed to deflated. To make sure the spongy erectile tissue retains blood, the body dilates, or widens, the blood vessels that carry blood to the penis (this is called vasodilation) and constricts, or narrows, the blood vessels that carry blood away from the penis (this is called vasoconstriction), just like a person turns on the faucet and plugs the drain when drawing a bath. More blood gets in the penis than gets out, and the result is a rapid gain in local blood volume and, in turn, engorged erectile tissue – put more simply, an erect penis.

What Viagra™, Levitra™, and Cialis™ Do

Viagra™, Levitra™, Cialis™ and other impotence treatments work by a process called selective inhibition. In selective inhibition, enzymes that normally latch on to and break down – effectively "turn off" – certain chemicals are prevented from doing so, making the effect of those chemicals last longer. In the case of erections, the chemical is a hormone called Cyclic GMP, and the enzyme responsible for stopping its action is called PhosphoDiEsterase, or PDE. Cyclic GMP is responsible for vasodilation; PDE is responsible for disposing of Cyclic GMP after it has done its job.

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